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We recently reported studies examining a novel glycolipid surfactant-peptide conjugation technology designed to prolong in vivo terminal elimination half-life (T 1/2 ) and demonstrated its tunable impact on pharmacokinetic (PK) parameters for analogs of both parathyroid hormone 19 and GLP-1R/GCGR dual agonists 20

We identified differences in chromatin accessibility, DNA methylation and histone modifications in the USC lines, which corresponded with differences in transcriptional responses affecting programmed cell death and cyclooxygenase-2 (Cox-2)-regulated inflammatory responses that impact rUTI susceptibility

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