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To differentiate between the potential involvement of these two consequences in H 2 O 2 -induced sensitization to TNF hepatotoxicity, we first exposed HepG2 cells to (BSO), a potent inhibitor of gamma-glutamylcysteine synthetase, the rate-limiting enzyme in the glutathione synthesis pathway (Fig

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Their Cryo-TEM images show uniformly distributed liposomes in multiple configurations: unilamellar (single-layer), multilamellar (multiple layers), and multivesicular (compartmentalized internal structures)