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Vegans and Vegetarians: B12 is found almost exclusively in animal products, so those on plant-based diets must use fortified foods or supplements Older Adults: reduced stomach acid can decrease B12 absorption from food as we age People with Pernicious Anemia: this autoimmune condition prevents the body from making intrinsic factor, a protein needed for B12 absorption Individuals with Gastrointestinal Conditions: diseases like Crohn's or Celiac disease can impair nutrient absorption Patients Who Have Had Gastric Surgery: procedures like gastric bypass can reduce the body's ability to absorb B12 Certain Medications: drugs such as Metformin and proton pump inhibitors (PPIs) can interfere with B12 absorption Medically-Approved vs
Applications in Research As a standard diluent for peptide and protein reconstitution Preparation of injectable-grade research compounds for in vitro or ex vivo studies Investigation of peptide and biologic stability following reconstitution Formulation testing and solvent compatibility studies Multi-use experimental workflows requiring bacteriostatic protection Specifications Summary Purity: Manufactured to specification Appearance: Clear, colourless sterile solution Solvent Type: Bacteriostatic aqueous diluent Preservative: Benzyl alcohol 0.9% (w/v) Solubility: Fully miscible with water and aqueous buffers Storage: Controlled room temperature Pack Size: 10 ml Handling, Use & Stability Use aseptic technique when accessing vial contents Avoid contact with non-sterile surfaces Do not use if solution becomes cloudy or discoloured Seal vial promptly after use to maintain sterility Avoid exposure to excessive heat or prolonged light Do not freeze Precautions & Notes Not all peptides or biologics are compatible with benzyl alcohol
1419) (Diagen, Ljubljana, Slovenia) dissolved in 0.9% NaCl was used in all experiments [1,2,3,4,5,6,7,8,9,10,11]
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Rapid intravenous injection may result in cardiac arrhythmias
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