semaglutide experience reddit My thoughts after 12 months on Wegovy (and a weight loss of 88 lbs) : r/ Experiences switching from semaglutide to

A downward trend in the weekly average is what matters

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Others switch to a higher concentration like 5mg/mL once they reach maintenance dosing to keep unit measurements more manageable, though this requires ordering a new vial mixed at the different strength

The medication should be injected subcutaneously into the abdomen, thigh, or upper arm, with rotation of injection sites to prevent lipodystrophy or persistent local reactions

Mechanism of action Semaglutide is a GLP1 analogue with 94% sequence homology to human GLP1 that selectively activates GLP1 receptors, the same receptors engaged by endogenous GLP1 secreted from intestinal Lcells in response to nutrient ingestion