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Once daily injection of exendin-4 to diabetic mice achieves long-term beneficial effects on blood glucose concentrations

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It is prescribed for individuals with a BMI (Body Mass Index) of 27 or higher, provided they have weight-related conditions such as Type 2 Diabetes, High Blood Pressure, and Sleep Apnea

Additionally, GLP-1R signaling in -cells activates mTOR-dependent transcription of hypoxia-inducible factor 1 alpha (HIF-1), which upregulates glucose expression and promotes glucose metabolism [8, 9]

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