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By contrast, inflammation, and especially low-grade inflammation, as well as dysregulated immunity (e.g., altered leucocyte counts as well as cell-mediated immune responses), is shared between AUD and obesity, contributing at multiple levels to their related medical complications, but also representing potential treatment targets [40, 41]

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Studies show that CrAT overexpression in primary human skeletal myocytes increases glucose uptake and attenuates lipid-induced suppression of glucose oxidation, demonstrating the importance of carnitine-dependent metabolic pathways in preserving insulin sensitivity and metabolic health

PatentUS20200283424A1

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