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For the estimated 1.5 million Americans living with lupus, and millions more worldwide, conventional treatments often involve a difficult tradeoff: suppress the immune system broadly to reduce attacks on healthy tissue, but leave the body vulnerable to infections and long-term complications

Each method offers distinct advantages and considerations that can significantly impact treatment outcomes

Damaged hepatocytes release ROS into the extracellular environment, thereby activating ROS-generating hepatic stellate cells

Continued research is needed to improve response prediction and optimize personalized pharmacotherapy

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