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Verzenio (abemaciclib) Disease area(s): Oncology Manufacturer(s): Eli Lilly and Company 2024 Sales (USD): $5.31 billion Why it sold so well: In 2024, Eli Lillys treatment for HR-positive, HER2-negative breast cancer, Verzenio, experienced substantial sales growth, with global revenues increasing by 36% year-over-year to $1.56 billion in the fourth quarter, and $5.31 billion for the full year, an increase of 37% from the previous year

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Under 503A, a state-licensed compounding pharmacy can prepare patient-specific semaglutide or tirzepatide formulations when a prescriber documents a clinically significant difference from the commercial product, for example an intolerance-driven microdose titration or a preservative-free formulation

Incretin hormones GLP1 and GIP normalize energy utilization and reduce inflammation in the brain in Alzheimer's disease and Parkinson's disease: from repurposed GLP1 receptor agonists to novel dual GLP1/GIP receptor agonists as potential diseasemodifying therapies

The progress that felt inevitable three months ago now feels like a distant memory