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Consequently, despite substantial upfront investment, state Medicaid programs may realize limited long-term cost savings or offsets, as treatment discontinuation reduces the likelihood of durable health and economic gains

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The compound operates through a unique triple mechanism: inhibiting the reuptake of norepinephrine (NET), dopamine (DAT), and serotonin (SERT) transporters with IC50 values of 1.7 nM, 65 nM, and 11 nM respectively

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