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Serious side effects that require immediate medical attention include: Allergic Reactions : Manifested as skin rash, itching, hives, or swelling of the face, throat, lips, or tongue

doi: 10.1016/j.yrtph.2006.06.003

Acknowledgements The authors thank the research resource division (RRD) (RIKEN Center for Brain Science) and RIKEN CBS-EVIDENT Open Collaboration Center (RIKEN Center for Brain Science) for technical assistance, Yukiko Nagai (RIKEN Center for Brain Science) for secretarial work, Kenichi Nagata (Nagoya University) and members of the Laboratory for Proteolytic Neuroscience (RIKEN Center for Brain Science) for beneficial suggestions

In addition to targeted blends, many nutraceuticals are formulated as methylated multivitamins