Zhou et al., 2025)
For example, in certain embodiments, a sustained and/or extended release formulation described herein comprises a combination of poloxamer 407 (pluronic F127) and carboxymethylcellulose (CMC) in a ratio of about 40:1, about 35:1, about 30:1, about 25:1, about 20:1, about 15:1, about 10:1, or about 5:1.4%, about 4.5%, or about 5% of the total weight of the formulation or composition
Loading phase (with neurological symptoms): 1mg on alternate days until there is no further improvement, then every two months
However, intravenous infusion bypasses these barriers, allowing for the direct delivery of high doses of Vitamin C into the bloodstream
Habets JGV, Heijmans M, Kuijf ML, Janssen MLF, Temel Y, Kubben PL