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Maintaining healthy B12 levels can support stress and emotional balance, as it aids in producing mood-regulating chemicals like dopamine and serotonin

If a pregnant patient has a documented deficiency of one or more B vitamins or a condition like hyperemesis that prevents oral intake, the benefits of correcting the deficiency (preventing serious maternal and fetal complications) outweigh any minimal risk from the injection

The Human Microbiome Project Consortium.Structure, function and diversity of the healthy human microbiome

Intrinsic factor, Medline Plus, Vitamin B12, Fact Sheet for Consumers, National Institutes of Health, Office of Dietary Supplements, Vitamin B12, Fact Sheet for Health Professionals, National Institutes of Health, Office of Dietary Supplements Pawlak R

Even with a well-structured diet and oral supplementation, certain nutrients may not reach adequate levels in patients with absorption limitations, increased physiological demand, or documented deficiency