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Vomiting, diarrhea, and constipation stem from altered gut motilitythe speed at which food moves through your digestive tract

Hyperoxaluria develops in 5% of patients taking large doses

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Approval was backed by the ATTAIN program, including ATTAIN-1 (n= 3127), where Foundayo showed weight loss of 27.3 lbs (12.4%) vs 2.2 lbs (0.9%) with PBO at the highest dose, with overall loss of 25 lbs (11.1%) vs 5.3 lbs (2.1%), alongside reductions in CV risk markers across all doses About Foundayo (orforglipron) Foundayo is a once-daily small molecule (non-peptide) oral glucagon-like peptide-1 receptor agonist that can be taken any time of the day without restrictions on food and water intake

If you take certain medications: Talk with your clinician before taking berberine if you take medications, including diabetes meds or insulin, anticoagulants or antiplatelets, or drugs metabolized by CYP3A4/P-gp