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In the UK, B12 replacement is typically administered via intramuscular hydroxocobalamin injections for patients with confirmed deficiency, particularly those with malabsorption or pernicious anaemia, as specified in the BNF and NICE CKS guidance on B12 and folate deficiency anaemia
How Gastric Banding Affects Vitamin B12 Absorption Gastric banding leaves the B12 absorption pathway anatomically intact, so deficiency is driven by dietary restriction and PPI use rather than surgical bypass
High-strength capsule products require serious attention to consistency, manufacturing standards, and documentation review
How to be rational in practice
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