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used a hydro-alcoholic extract of Moringa to treat experimental colitis in mice, and observed downregulation of a group of secreted inflammatory factors and an increase of both colon lengths and the expression of glutathione-S-Transferase Pi 1 (GSTP1), which is a detoxifying enzyme mediated by NFE2-Related Factor 2 (NRF2) ( Chronic inflammation is also associated with metabolic disorders, such as non-alcoholic steatohepatitis (NASH) caused by hepatic lipid accumulation, and high-fat diet induced glucose intolerance

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As a chronic oral inflammatory disease closely related to systemic diseases, the establishment of the relationship between periodontitis and metabolic diseases will reveal the relationship between periodontitis and metabolic diseases, and promote the development of treatment and prevention of periodontitis and hyperuricemia

[DOI] [PubMed] [Google Scholar] 73.Fioravanti M., Nakashima T., Xu J., Garg A