select trial semaglutide nejm Phase 3 of in Metabolic Dysfunction–Associated Steatohepatitis Beyond obesity: Novo's SELECT re-defines

To overcome drug resistance and enhance its cytotoxicity, two derivatives of DOX were synthesized incorporating a sulfonamide moiety: 4-mononitrobenzenesulfonyl DOX (MNS-DOX) and 2,4-dinitrobenzenesulfonyl DOX (DNS-DOX) 94

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Schwartz GG, Steg PG, Szarek M, Bhatt DL, Bittner VA, Diaz R, Edelberg JM, Goodman SG, Hanotin C, Harrington RA, Jukema JW, Lecorps G, Mahaffey KW, Moryusef A, Pordy R, Quintero K, Roe MT, Sasiela WJ, Tamby JF, Tricoci P, White HD, Zeiher AM, Committees OO

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Riegler H, Geserick C, Zrenner R (2011) Arabidopsis thaliana nucleosidase mutants provide new insights into nucleoside degradation