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In addition, the increased expression and activity of NOX and xanthine oxidase and NOS becoming uncoupled and structurally unstable also lead to increased ROS production [8]

Song Y, Zhang S, Zhao N et al (2024) Pseudomonas aeruginosa two-component system CprRS regulates HigBA expression and bacterial cytotoxicity in response to LL-37 stress

Fluorescence microscopy studies have documented rapid cellular accumulation, with detectable intracellular concentrations within 30 minutes of external application at physiological concentrations

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