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Core-state emission results from quantum confinement in sp 2 domains, where decreasing particle size leads to blue-shifted emission due to wider band gaps, while larger conjugated domains yield red shifts [Figure 1BI)

In patients with Leber's disease, administration of cyanocobalamin may cause acute and rapid atrophy of the optic nerve

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Absolutely, but I try to keep things very visual in describing, and not pull you into the weeds of deep biochemistry