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In hindlimb ischemia models, the peptide accelerates blood flow recovery as measured by laser Doppler scanning, with histological analysis confirming increased vessel numbers and enhanced vascular expression of VEGFR2

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Many therapies now considered foundational in perioperative medicine were initially adopted based on mechanistic plausibility and early observational signals before high-quality surgical outcome trials were performed

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Small amounts of [ 3 H]BPC157 were detected in feces, accounting for 0.63% (female) and 2.26% (male) of the total fecal radioactivity