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Bone Health If your body lacks B12, your skeleton may suffer: in a study published in the Journal of Bone and Mineral Research (4), low B12 was linked with poor bone mineral density, suggesting a role for the vitamin in bone formation

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If your homocysteine level is high, you dont have enough B12, folate, and vitamin B6

These effects are particularly noticeable in individuals with a B12 deficiency or conditions like chronic fatigue syndrome or anemia, where long-term treatment can significantly improve quality of life

Vegans and vegetarians may not get enough B12 from their diet