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Regulatory status will remain contingent on new data and prevailing evidence standards, as well as the absence of approved therapeutic uses to date

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Notably, in most countries PAC is freely sold as an OTC drug, raising the risk of unintentional abuse and increased adverse effects ( No answer can be given to the above open questions because PAC efficacy/adverse effects, unlike most of the drugs repositioned for COVID-19 therapy, have not yet been evaluated in controlled clinical trials or analyzed through retrospective analyses

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Therefore, it is known that, in some cases, where the liver is unable to perform effectively (whether it be from clinical disease, medications, alcohol abuse, protein digestion issues such as leaky gut, lack of stomach acid (PPIs), NFLS or gluten intolerance), the build-up of toxins and the use of amino acids for detoxification could suffer, as the availability of amino acids for its functionality is challenged