The drug degraded under certain preparation conditions, limiting available processing options
Banuls C, Rovira-Llopis S, Martinez de Maranon A, Veses S, Jover A, Gomez M, Rocha M, Hernandez-Mijares A, Victor VM (2017) Metabolic syndrome enhances endoplasmic reticulum, oxidative stress and leukocyte-endothelium interactions in PCOS
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However, translating this substantial preclinical rationale into clinical practice necessitates rigorous, large-scale randomized controlled trials to substantiate their efficacy and safety in human populations
The drug also significantly reduced the rate of moderate or severe exacerbations, while prolonging the time before patients experienced their first exacerbation episode