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Impaired thymidylate synthesis, which leads to faulty DNA synthesis, is responsible for megaloblastic and macrocytic anemias
Lenny Macrina: Right, and they talk about swelling, joint pain, anxiety, panic attacks, heart palpitations, insomnia, drowsiness, weakness, fatigue, loss of appetite, depression, anhedonia
Treatment of bEnd.3 cells with rTGF 1 led to a significant suppression of claudin-5 mRNA expression (Figure 4a)
Most side effects are dose-dependent, especially nausea and gastrointestinal disturbances
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