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Figure from van der Aart-van der Beek AB, Nat Rev Nephrol, 2020 The Study Methods This was an international, event-driven, double-blind, parallel-group, randomized, placebo-controlled trial conducted at 387 sites in 28 countries comparing semaglutide to placebo in patients with T2DM and CKD, both being treated with baseline standard of care

This one-week washout period applies regardless of what dose of Mounjaro youre currently taking

A GLP-1 analog is a modified version of the naturally occurring GLP-1 hormone made by our bodies

This approach extends the ramp-up period significantly but can dramatically reduce the GI side effects that cause many patients to abandon treatment early

Many people find weekly injections more convenient and easier to maintain long-term than daily ones