If youre planning pregnancy: If you need to use compounded, choose an FDA-registered 503B facility (these have better oversight) rather than regular 503A pharmacies Keep detailed recordswrite down exactly what youre taking, the concentration, the dose, everything
Starting low and escalating gradually produced fewer gastrointestinal side effects than starting directly at a higher dose, which is why the 2mg +2mg-every-4-weeks schedule became the standard escalation approach in the published data
When made according to federal laws, compounded drugs do not require FDA approval and are exempt from undergoing safety, effectiveness, or manufacturing reviews
Nobody is having an honest conversation about this topic, so allow me to be the icebreaker here
Recombinant PNPLA3 protein shows triglyceride hydrolase activity and its I148M mutation results in loss of function