A demethylase, also known as the eraser, can remove m6A ( Increasing evidence has shown the vital role of regulating gene expression played by m6A through affecting mRNA degradation, RNA stability, translation, microRNA maturation, alternative splicing, and cytoplasmic mRNA conversion ( However, abnormal m6A modification is related with tumorigenesis, embryonic developmental disorders, immune cell homeostasis and differentiation failure, and neurological system diseases ( FTO is the first identified protein to catalyze the demethylation of m6A ( Materials and Methods Human PTC Clinical Tissue Sample In total, 86 PTC tissues and adjacent non-cancerous tissues were obtained from PTC patients receiving standard resection without radiation therapy at the First Affiliated Hospital of Zhengzhou University from 2020 to 2021
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