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In first-in-human (FIH) clinical trials, biologics are usually administered by IV injection or infusion for various reasons, such as ensuring 100% bioavailability

A patient who experiences side effects early, changes jobs, loses discretionary income, or simply decides the program is not a fit may care more about refund flexibility than about the lowest possible annualized medication rate

doi: 10.1111/j.1467-9868.2010.00746.x 31

Stick to a simple, calming routine and let your skin heal before reintroducing your stronger products

Reporting Requirements: Research protocols often have specific requirements for reporting adverse events