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## After First Use: The 56-Day Window Once you break the seal on a semaglutide pen or puncture a vial with a needle, a countdown begins

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Patients should maintain regular contact with their diabetes care team and report any concerns about hypoglycaemia, particularly if taking GLP-1 medications alongside other glucose-lowering agents such as sulphonylureas or insulin

It will also serve as a convenient spot for morning coffee and casual lunches.

What the Research Says About Combining Semaglutide With Lifestyle Changes The evidence is clear: semaglutide works best when you pair it with diet and exercise