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This low-grade systemic inflammation: Impairs insulin receptor signalling, directly worsening insulin resistance Damages ovarian granulosa cells, impairing egg development and ovarian function Disrupts gut barrier integrity, contributing to what some researchers call a "leaky gut" pattern associated with systemic inflammation Amplifies HPA axis dysregulation, raising cortisol and further disrupting sex hormone balance Chronic inflammation is both a consequence of PMOS and a driver that perpetuates it

When your glutathione levels are high, your liver works more efficiently, which means fewer toxins hanging around in your body

Cerebrospinal fluid (CSF) Cerebrospinal fluid that bathes the brain and spinal cord, and is thought to contain circulating factor(s) that contribute to MS pathophysiology

Computationally, the cerebellum also plays a role in predicting sensory consequences of movements by calculating prediction errors that eventually alter subsequent movements