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23 : 27122718 Connolly T, Carruthers A, Melchior D

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Platelets were traditionally considered to play a greater role in arterial rather than venous thrombosis, but platelets have been shown to have a role in venous thromboembolism (VTE) by inducing the formation of neutrophil extracellular traps, releasing proinflammatory mediators and microparticles, and aggregating as a component of thrombi themselves [27]

Anti-CXCL10 antibody treatment completely reversed these changes, suggesting that CXCL10 is a key cytokine impairing ovarian function