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If you are pregnant: Compounded GLP-1s should not be used during pregnancy

Much of this early weight loss is actually water weight, not fat, as your body uses up stored glycogen (a carbohydrate reserve in your muscles and liver) that holds onto water

It found that between 2022 and 2023, as prescriptions for GLP-1 drugs more than doubled, rates of bariatric surgery fell by 8.7%

Standard titration is 4-week increments for good reason

As well as endogenous GLP-1,GLP-1 receptor agonists also have numerous other effects such as promoting weight loss, deceleration of gastric emptying, lowering blood pressure (systolic and diastolic), and lowering total cholesterol ( Figure 1