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Safety: The most common side effects are mild gastrointestinal symptoms, such as nausea or diarrhea, which typically improve with time

Sustainable weight management requires patience, professional support, and evidence-based interventionsnot unproven combinations that may compromise safety and long-term success

In some cases, a lower-dose approach may be appropriate

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Gao L, Lee BW, Chawla M et al (2023) Tirzepatide versus insulin glargine as second-line or third-line therapy in type 2 diabetes in the Asia-Pacific region: the SURPASS-AP-Combo trial