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Glutamate accumulation to micromolar levels [375] results in GluN2B-mediated NMDA receptor overactivation, Ca 2+ overload, and subsequent tau hyperphosphorylation and dendritic spine collapse [376], linking excitotoxicity to amyloidogenesis [28]

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General warnings Other uses Oxoneg 500 Tablet may also be prescribed for indications other than those stated above in certain specific circumstances, especially if other medicines are not effective

The bulk of the energy produced by the kidney is used to fuel transepithelial reabsorption and secretion transport processes in the renal tubule