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In vitro cellular senescence models (such as senescence models of human fibroblasts, hepatocytes, and nerve cells) are common tools for studying aging mechanisms and interventional drugs

The weight-adjusted approach matters more for peptides with narrow therapeutic windows or those where body composition significantly affects distribution

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If any oral hypoglycemics are used during breastfeeding, the nursing infant should be monitored for signs of hypoglycemia, such as increased fussiness or somnolence