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The key transcription factors and substrates related to gluconeogenesis have been shown to be involved in liver regeneration

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doi: 10.1016/S0140-6736(82)91330-7 78 CappadoroMGiribaldiGOBrienETurriniFMannuFUlliersDet al

This makes it relevant not just for hypertrophy but also for long-term skeletal support

In this study, we hypothesized that FOXO4-DRI treatment could remove the senescent cells in the expanded chondrocytes, thus enhancing their potential in generating high-quality cartilage