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Short-term supplementation of celecoxib-shifted butyrate production on a simulated model of the gut microbial ecosystem and ameliorated in vitro inflammation

Matsushita N, Ishida N, Ibi M, Saito M, Sanbe A, Shimojo H, Suzuki S, Koepsell H, Takeishi Y, Morino Y, Taira E, Sawa Y, Hirose M (2018) Chronic pressure overload induces cardiac hypertrophy and fibrosis via increases in SGLT1 and IL-18 gene expression in mice

These animals suggest that APAP-mediated injury in the Drosophila fat body is sufficient to induce cell death and a regenerative response

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The article describes this combination as amplifying nausea, diarrhea, or constipation, and notes that roughly 10 to 15 percent of post-surgical patients already live with chronic bile reflux or diarrhea