Ozempic for CKD and heart disease The FLOW phase 3b clinical trial (NCT03819153) demonstrated that when Ozempic 1 mg injection was used in adults with type 2 diabetes and CKD, Ozempic demonstrated: 24% reduced the risk of kidney disease progression, kidney failure, and cardiovascular death at 3 years when compared to placebo
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Other factors, including patient age, gender, body mass index (BMI), and hepatitis C infection, further exacerbate the risk of PTDM. Current management of PTDM remains a challenge, often requiring adjustment immunosuppressant regimens and promoting lifestyle changes
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The International Union of Basic and Clinical Pharmacology, The British Pharmacological Society, The University of Edinburgh