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In this regard, increased loss of glutathione may change the intracellular environment to a prooxidant state and thereby caused prominent changes in gene expression, which is ultimately evolving into a malignant state [26]

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Unfavorable environmental conditions result in the formation of reactive oxygen species (ROS) in different subcellular compartments, which may intracellularly activate anti-oxidants (e.g., key player GSH) and defense responses leading to plant acclimation

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