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in these populations, even modest muscle loss can precipitate functional decline, induce metabolic adaptations that predispose them to weight regain [9, 10], and increase the risk of sarcopenic obesity [2]

Direct answer: Animal studies showed thyroid tumors, but human risk remains unclear and appears low

Moving on to the reasons behind this choice, we can suggest that the type fits the companys business model

Similarly, recruitment of participants with severe hepatic impairment into the hepatic impairment study was challenging and, despite a third study site being added and the recruitment period being prolonged, it was not possible to complete recruitment of seven participants into the severe hepatic impairment group