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Exosome formation increased after GPX4 inhibition, which contained prominin and TSG101, as well as ferritin, while blocking the export of exosomes resulted in the accumulation of iron, indicating that in the state of cellular oxidative stress, prominin 2 can promote the formation of iron-containing exosomes and transport intracellular iron to the extracellular space, thereby enhancing cell resistance to ferroptosis [75]

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Published December 12, 2023.

It can be given in divided doses with meals, or as an extended-release formulation (Glucophage XR ) that is generally given once daily with the evening meal

Therefore, it has been suggested that L-carnitine supplementation could potentially improve energy metabolism and alleviate depressive symptoms associated with mitochondrial dysfunction