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The first step in caffeine CYP1A2 metabolism is 3demethylation, which results in 1,7dimethylxanthine (paraxanthine), which accounts for approximately 84% of the major caffeine metabolites

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Against other GLP-1 receptor agonists, the relative risk was 1.08, essentially identical, with a confidence interval of 0.12 to 9.72

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