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Recent studies have found that circulating TMAO can promote vascular calcification in rats with CKD and activates the NLRP3 inflammasome and NF-B signaling pathways (Zhang et al., 2020)

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Paterson RW, Brown RL, Benjamin L, Nortley R, Wiethoff S, Bharucha T, et al

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Seizures, microcephaly Microcephaly A congenital abnormality in which the cerebrum is underdeveloped, the fontanels close prematurely, and, as a result, the head is small

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41 Several molecular mechanisms synergistically act to impair the structural function of the heart and promote the development of DHD (Fig

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