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Assuming they started out at 35 or 40% body fat, they're actually getting slightly higher in fat percent

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Morning tiredness tends to be worst during this phase as the body copes with both dose escalation and a growing calorie deficit

also discovered this mechanism in a high-fat diet rat model, there is a reduction of the NOD-like receptor family, pyrin domain containing 3 inflammasome (NLRP3) and caspase 1 (Zhang et al., 2018)