ICD-10 code for chronic muscle spasms is M62.838 (muscle spasm, other site)
Early research has focused on its potential role in tissue repair and protective mechanisms within the digestive system
While not directly sleep-related, systemic inflammation is a well-established disruptor of sleep quality Autoimmune myocarditis (FASEB J, 2017) -- attenuation of disease via Treg generation, further establishing anti-inflammatory potential Structure-activity studies (Nature Communications, 2021) -- investigation of analogs with improved selectivity, suggesting potential future clinical development No human studies have been conducted for cortistatin in any indication, including sleep
The gut microbial species composition is diverse and varies among individuals
Jang SW, Liu X, Chan CB, Weinshenker D, Hall RA, et al