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The results showed that compared to placebo, GLP-1 receptor agonists reduced the risk of kidney failure by 16% and the worsening of kidney function by 22% (defined by a drop in estimated glomerular filtration rate a measure of how much blood the kidneys filter clean every minute of at least 50%)

doi: 10.1016/j.jacc.2007.07.016 100 NiebauerJYolkIDKempMDominguezMSchumannRRRauchhausMet al

Moreover, in a prospective study, reduced glutathione administered alongside blood purification therapy significantly decreased endotoxin levels, inflammatory mediators, and hepatic injury in septic shock patients (Liu and Meng, 2024)

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