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Both medications are very effective at controlling blood sugar levels and aiding in weight loss, with retatrutide showing a small advantage in trials, but tirzepatide has more long-term data as its already been FDA-approved

GLP-1 drugs may reshape brain's dopamine reward system Beyond weight loss, research is pointing to broader effects on the brain

1 Women aged 18 to 29 years had a significantly higher prevalence of sunless tanning (21.2%) compared with women aged 30 to 39 years (16.5%) and 40 to 49 years (14.9%) ( p =0.004)

Impairment of vitamin B 12 absorption can cause megaloblastic anemia and neurologic disorders in deficient subjects