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These additional effects are absent or minimal with the MC1R-selective Melanotan I Nasal Spray

The effects of ANP on lipolysis are more relevant to primates than rodents, as rodents express over 100 times the level of the clearance receptor NP clearance receptor (NPCR), which mitigates the effect of ANP on lipolysis (112, 113)

During the period from d 42 ap to d 56 pp , 99% of all PMN could be activated by TPA ( Figure 5F )