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Mice fed a MCD diet presented NASH-like features such as steatosis and inflammation 22,23 , assessed by the histopathological evaluation of the NAS score, intrahepatic TG accumulation, elevated ALT and increased Fgf21 mRNA levels (Fig

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Exendin-phe1 outperforms other GLP-1R agonists We next compared the pharmacological characteristics and beta cell actions of exendin-phe1 with those of other clinically approved GLP-1R agonists, including Lixisenatide, Liraglutide, Semaglutide, and Dulaglutide