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Eating well, exercising, managing stress, and quitting smoking can help

Medicare, through Part D, currently covers the medications only for patients with type 2 diabetes, obstructive sleep apnea, or noncirrhotic metabolic dysfunction-associated steatohepatitis

Healthcare systems can implement additional safeguards, including electronic prescribing systems with built-in dose range checking, patient education materials in multiple formats (written, video, pictorial), and follow-up contact after initiation or dose escalation to assess tolerance and adherence

Zofran can cause drowsiness or a feeling of fatigue in some people

It is also clear that these strategies are not being used optimally