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Importantly, the serine thus produced can be converted to glycine via serine hydroxymethyltransferases concomitantly charging the folate pool with one-carbon units

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Importantly, GH isnt secreted in a steady drip

The childhood-onset obesity is also a trigger for severe complications during adult age, in particular body composition and endocrine alterations [8, 9], including growth hormone (GH) deficiency (GHD) [9], hypothyroidism [10], hypogonadism [11], and leptin resistance [12]